Saturday, September 19, 2009

Biotech and Nanotech: Novel Cancer Killers


From Al Fin:

Until recently, physicians have had to rely on "sledge hammer" treatments for fighting cancer: surgery, radiation, chemotherapy. All three mainstream approaches to cancer therapy can kill the patient, or have devastating effects on the person's quality of life above and beyond any impact from the cancer. Both doctors and patients would like access to finely targeted therapies that kill only the cancer, and leave the patient whole and healthy. Both biotech and nanotech (as well as the two combined) offer hope for such "magic bullet" therapies.

Specialists at the Curie Institute in Paris have devised a method of "baiting" cancer cells into killing themselves, using special DNA decoys.

North Carolina State University researchers are using modified plant viruses coated with targeting molecules to selectively target and destroy cancer cells.

UC Santa Cruz researchers are coating hollow gold nano-spheres with short-chain targeting molecules that bind to cancer cells. Infrared light beamed onto the tumour is trapped by the gold particles, and the cancer cells are cooked.

Tel Aviv University researchers are building nano-submarines out of phospholipids, filling them with siRNA particles that shut down the target cell's cell division machinery, and coat them with specific targeting molecules.

German researchers are injecting nano-magnetic particles of iron directly into tumours, then using an extermal oscillating magnetic field to induce a killing heat inside the cancer.

You can see how the convergence of nanotech and biotech is aiding researchers in their highly specific targeting of tumour cells, and other cells of interest (over-active immune cells in autoimmune disorders). Some of these treatments require the application of external energy (infrared light, magnetic fields, heat, etc), and other approaches insert the killing impetus inside the nanoparticle itself. Most of the methods use bio-targeting molecules to guide the nanoparticle to the cells of interest.

This is only the beginning. As long as the entire economic infrastructure of the western world is not destroyed by the neofascists currently reigning in Washington, resources will continue to find their way to productive researchers. The pace of discovery may slow, as more resources are diverted to non-productive government programs as well as to politically connected crony-friends of the reich. It is quite possible that even after cleaning out the rat's nest through future elections, recovery from the current spree of corrupt dysfunction may take many years, or decades.

19 comments:

jeppo said...

OT

Pastorius, I just read this article by Fjordman over at GoV about the evolution of human intelligence. Just thought you might be interested.

LL said...

I'd so rather see resources spent here than for money pits like ACORN (and their network of parasites).

Good post!

christian soldier said...

P-thank you --thank you---

the information in this post is going to give a lift to many--some I know personally..
The 'slippery slide' has stopped--an 'avalanche' has started--people are waking up---
It may not take as long as you think!!!
C-CS

Pastorius said...

I don't know about Fjordman, but here's my theory of human mental anthropology.

Environment breeds man's experience with the Earth

Man's experience with the Earth breeds Religion

Religion breeds Culture.

Culture breeds a theory of knowledge (epistemology).

A theory of knowledge breeds a respect, or lack of respect for scientific and artistic inquiry.

Respect for scientific and artistic inquiry breeds innovation and creativity.

Innovation and Creativity breed a myriad of intelligences, most of which can not be measured by any standardized test.

I think Fjordman is, sadly, a much more reductive person in his theory of human mental anthropology.

He is much more learned than I. However, he seems to be rather simplistic in his view of the world many times.

But, I will read his essay.

Epaminondas said...

You people are all ridiculous.

If you are 25 and get cancer, MAYBE the resources will exist to help you, if you know someone, and if as Ezekiel Emanuel put it, (paraphrase) ..'if the times requires the govt to decide whose social value(s) or reward justifies it' - puts you thru the right door...

But if you are a typical 72 and get that kind of leukemia, sorry, we've decided that since the chemo and bone marrow transfers can at best give you a single remission of 11-13 months, and the nanotechnology treatment is so expensive and longer term for bone marrow treatment, actually we have good news we're sending you right home with a prescript to enjoy yourself heartily for 5-8 weeks

While at the low end scientists do what they do, it will become increasingly clear that to the only funding agency left, the one that pays for the research, regulates all devices and drugs, all of this is for the purpose of advancing society as a whole in a distinct and particular way.

Never let a crisis go to waste?

No opportunity to advance that social justice view will EVER be allowed to go to waste

Pastorius said...

Epa,
As Al Fin so eloquently wrote:

"This is only the beginning. As long as the entire economic infrastructure of the western world is not destroyed by the neofascists currently reigning in Washington, resources will continue to find their way to productive researchers."

jeppo said...

Fjordman is basically comparing and contrasting two opposing theories of human civilizational advancement.

To Jared Diamond, everything can be explained by geography and environment. Michael Hart expands on this by explaining the crucial role of human intelligence in technological progress. Fjordy also mentions Harpending and Cochrane's book "The Ten-Thousand Year Explosion", which posits that human evolution has actually been accelerating in the past 10,000 years.

Even though Diamond's "Guns, Germs and Steel" is one of the most important anthropological books ever written, its great flaw is that completely ignores differing levels of human intelligence, except that Diamond ludicrously claims that headhunting cannibal Papua New Guineans are smarter than white people. I guess he felt he had to burnish his PC credentials by getting in the usual, seemingly mandatory anti-white digs.

Anyway the comments over there have somewhat shifted to the subject of what exactly constitutes "The West". I left a comment with my own definition and recommendations. C'mon over and join in the fun!

Pastorius said...

See what I mean, Jeppo.

The ideas of neither Diamond or Fjordman are as complex as mine. Once again, it is a given that Fjordman is more learned than I am. It's hard for me to argue with him, for that reason.

Additionally, I am certainly no expert in Anthropology or the history of the human mind.

I studied Philosophy, Literature and Religion in school. And, I have read a lot of Carl Jung, Rollo May, Joseph Campbell, and a bit of Freud.

Additionally, I have read all of Nietzsche's books multiple times.

I arrive at my thoughts on the basis of that background.

I believe the evolution of the human mind is very complex. It is not, in my opinion, reducible to environment or intelligence.

Frankly, that is a laughable notion to me.

By the way, here's a story which shows how MORMON culture effects a particular Samoan:

http://www.npr.org/templates/story/story.php?storyId=112970742

I see this kind of stuff all the time.

It's kind of lame for me to give you an individual story to prove a larger idea, but unlike Jared Diamond, Fjordman, and the people at VDare, I am not obsessed with theories of race.

I only get into these discussions because they are brought up to me.

jeppo said...

Well if it's any consolation, I'm sure that you're a lot more learned than me, but that's kind of a back-handed complement :)

I like Mormonism. Sure it's a bunch of phony prophecies dreamt up for the self-aggrandizement of its founder, noted fraudster Joseph Smith. But it works for the people who follow it, they tend to be exemplary citizens. IMHO Mormons make the best Americans, and probably the best Pacific Islanders too.

Diamond is a typical PC thug when it comes to attacking white people, while Fjordy defends whites. Not much in common there.

As for VDARE (my favourite website BTW), I see that the Blogger That Shall Not Be Named is now attacking them relentlessly as racists. What he doesn't understand is it's a coalition of immigration reformers, including conservatives, liberals, Democrats, Republicans, white nationalists, American Indian activists, environmentalists, etc. VDARE is a big tent with lots of differing viewpoints. But that's obviously far too subtle a distinction for the polemical BTSNBN.

Pastorius said...

Jeppo,
You said: I like Mormonism. Sure it's a bunch of phony prophecies dreamt up for the self-aggrandizement of its founder, noted fraudster Joseph Smith. But it works for the people who follow it, they tend to be exemplary citizens.


I say: I agree.


You say: Well if it's any consolation, I'm sure that you're a lot more learned than me, but that's kind of a back-handed complement :)


I say: I've read a lot in my lifetime, but I've also spent much of it in decadence and self-centeredness, so I am rather shallow in many ways. And, I don't much history other than American history. So, I'm a total idiot in that way.

By the way, I was confusing Jared Diamond with Jared Taylor.

Jared Diamond must be a real idiot if he thinks all intelligence comes out of culture. That is so reductionists, it's as if he and Fjordy are two babbling fools on the subject.

I gotta read this article.

Fjordman: It's all about how smart people are.

Jared: No, it's about their culture.

Fjordman: No it's not, and I can prove it. Look there's a bunch of smart people in Western Civ.

Jared: Yes, that's because of their culture.

Fjordman: No, it's cuz Western people are smarter than everyone else.

Jared: It's because they have a healthier culture.



I'm guessing it's not quite like that, though.


You said: VDARE is a big tent with lots of differing viewpoints. But that's obviously far too subtle a distinction for the polemical BTSNBN.


I say: I don't see it that way as you can imagine.

:)

I sure do seem to agree with CJ on a lot of stuff, considering the fact that I think he is, sadly, off the rails.

Pastorius said...

I'm reading the Fjordman article now. Finally getting some time to do it.

It is a good article.

Pastorius said...

Jeppo,
Remember the other day you and I were discussing where various nations rank in terms of patents. You gave me a link to a site.

I started to think about that link. Something was odd about it.

Then I realized Iran was on there, but Israel was not.

Also, it simply did not seem right that Latvia was leading and England was like 38th or something like that.

I checked with Al Fin, the writer of this post, and he said the numbers cited in that link do not at all match the numbers given in the United States Patent Office.

jeppo said...

Israel is #16 on that list. But I checked a couple other links and the patents-per-capita rankings are completely different, including one from the very same website, nationmaster.com.

So I don't know what to think about it except, Fuck you nationmaster.com!

And all this time I thought everything written on the internet was the God's honest truth. How disillusioning to find out that it just ain't so.

:(

Pastorius said...

Jeppo,
I know just how you feel.

I guess I will have to rethink all my assumptions as well.

Pastorius said...

Jeppo,
We need to find The World Economic Forum 2008-2009 WEF Global Competitive Index Report

Check this out:

http://www.ittn.org.il/news.php?cat=22&in=0

Pastorius said...

Here it is:

http://www.weforum.org/en/initiatives/gcp/Global%20Information%20Technology%20Report/index.htm

I haven't been able to figure out how to navigate my way around the thing yet.

Pastorius said...

Jeppo,
I've just finished reading Fjordman's essay. It is very interesting. It is hard for me to argue with his points. I don't know the facts on genetics, anthropology, or history.

I do believe, however, that it is a reductive/simplistic way of looking at a problem which is far more complex.

But, what the fuck do I know?

jeppo said...

There are so many different lists ranking nations by patents granted, competetiveness, technology, etc., and the different rankings are all over the map, that I don't know what to believe.

I think it's safe to say that Western nations, democratic East Asian ones, and Israel lead the pack, though whether the US, for example, is ranked 1st or 40th maybe depends on the biases of the list-makers...if that makes any sense.

That's the best Fjordman article I've read in quite a while, and apparently it's the first in a four-part series. Lately he's been writing lengthy four-part essays about the history of beer, wine, European music,

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Oops sorry, I fell asleep and did a faceplant into my keyboard thinking about how boring they were. I'm glad that Fjordy's back writing about interesting stuff once again.

nanotech said...

Nanotech has improved greatly in the past years, and it's helping many science fields, especially medicine.